{
    "created": "2021-07-02 08:21:48",
    "updated": "2026-06-20 15:57:57",
    "id": "0189a4ae-cf60-4675-a788-79d5caabab47",
    "version": 2,
    "ds_topic": null,
    "title_cn": "基于微剂量学蒙特卡罗模拟的重离子生物有效剂量精确计算方法",
    "title_en": "An accurate method for calculating biological effective doses of therapeutic heavy ions based on microdosimetric Monte Carlo simulation",
    "ds_abstract": "<p>该文章在蒙特卡罗(MC)模拟当中引入理想组织等效正比计数器(Ideal TEPC),采用Ideal TEPC与MC模拟方法对能量为330 MeV/u具有6 cm展宽Bragg峰(SOBP)的碳离子束生物有效剂量进行计算，结果显示Ideal TEPC结合MC模拟能够准确计算重离子的生物有效剂量,有效避免TEPC壁引起的辐射场畸变,结构材料所产生的δ电子对线能谱的影响,以及实验中位置的偏差,具有良好的移植性。</p>",
    "ds_source": "<p>数据来源于大量辐射生物学实验数据。</p>",
    "ds_process_way": "<p>Ideal TEPC与MC模拟方法</p>",
    "ds_quality": "<p>来源于实验研究，数据良好</p>",
    "ds_acq_start_time": "2019-01-01 00:00:00",
    "ds_acq_end_time": "2019-04-10 00:00:00",
    "ds_acq_place": "甘肃兰州",
    "ds_acq_lon_east": null,
    "ds_acq_lat_south": null,
    "ds_acq_lon_west": null,
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    "ds_share_type": "apply-access",
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    "ds_files_count": 2,
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    "ds_time_res": "",
    "ds_coordinate": "无",
    "ds_projection": "",
    "ds_thumbnail": "0189a4ae-cf60-4675-a788-79d5caabab47.png",
    "ds_thumb_from": 0,
    "ds_ref_way": "",
    "paper_ref_way": "",
    "ds_ref_instruction": "",
    "ds_from_station": null,
    "organization_id": "9971252d-7beb-4464-bc08-bdcc5a1d7dd1",
    "ds_serv_man": "敏玉芳",
    "ds_serv_phone": "0931-4967596",
    "ds_serv_mail": "ncdc@lzb.ac.cn",
    "doi_value": "",
    "subject_codes": [],
    "quality_level": 3,
    "publish_time": "2023-10-17 18:58:21",
    "last_updated": "2023-10-17 18:58:21",
    "protected": false,
    "protected_to": null,
    "lang": "zh",
    "cstr": "11738.11.NCDC.IMP.DB4031.2023",
    "i18n": {
        "en": {
            "title": "An accurate method for calculating biological effective doses of therapeutic heavy ions based on microdosimetric Monte Carlo simulation",
            "ds_format": "",
            "ds_source": "<p>The data come from a large number of radiation biology experimental data.</p>",
            "ds_quality": "<p>From the experimental study, the data is good</p>",
            "ds_ref_way": "",
            "ds_abstract": "<p>In this paper, the ideal tissue equivalent proportional counter (ideal TEPC) is introduced into Monte Carlo (MC) simulation. The ideal TEPC and MC simulation methods are used to calculate the biological effective dose of 330 MeV / u carbon ion beam with 6 cm Bragg peak (SOBP). The results show that the ideal TEPC combined with MC simulation can accurately calculate the biological effective dose of heavy ions, The distortion of radiation field caused by TEPC wall is avoided, and the distortion of radiation field caused by structural material is avoided δ The influence of electron on the line energy spectrum and the position deviation in the experiment have good portability.</p>",
            "ds_time_res": "",
            "ds_acq_place": "Lanzhou, Gansu",
            "ds_space_res": "",
            "ds_projection": "",
            "ds_process_way": "<p>Ideal TEPC and MC simulation method</p>",
            "ds_ref_instruction": ""
        }
    },
    "submit_center_id": "ncdc",
    "data_level": 0,
    "recommendation_value": 0,
    "license_type": "https://creativecommons.org/licenses/by/4.0/",
    "doi_reg_from": "reg_local",
    "cstr_reg_from": "reg_local",
    "doi_not_reg_reason": null,
    "cstr_not_reg_reason": null,
    "is_paper_in_submitting": false,
    "belong_to_nieer": false,
    "ds_topic_tags": [
        "微剂量学",
        "生物有效剂量",
        "微剂量动力学模型",
        "重离子治疗",
        "蒙特卡罗模拟"
    ],
    "ds_subject_tags": [],
    "ds_class_tags": [],
    "ds_locus_tags": [
        "兰州",
        "甘肃省"
    ],
    "ds_time_tags": [
        2019,
        2020
    ],
    "ds_contributors": [
        {
            "true_name": "肖国青",
            "email": "xiaogq@impcas.ac.cn",
            "work_for": "中国科学院近代物理研究所",
            "country": "中国"
        }
    ],
    "ds_meta_authors": [
        {
            "true_name": "肖国青",
            "email": "xiaogq@impcas.ac.cn",
            "work_for": "中国科学院近代物理研究所",
            "country": "中国"
        }
    ],
    "ds_managers": [
        {
            "true_name": "肖国青",
            "email": "xiaogq@impcas.ac.cn",
            "work_for": "中国科学院近代物理研究所",
            "country": "中国"
        }
    ],
    "category": "其他"
}