该文章通过功能影像PET-CT指导勾画食管癌靶区，比较不同影像勾画食管癌淋巴结的准确性，通过病理证实PET-CT勾画淋巴结优于CT。基于CT图像和PET/CT融合图像勾画肿瘤靶区及制定精确放疗计划，基于PET/CT融合图像靶区更精确，放疗更精准，避免了正常组织的过度损伤。CT联合PET-CT双重定位，功能影像的介入提高了靶区勾画的准确性。
", "ds_source": "研究的目的评是价18F-氟脱氧葡萄糖正电子发射断层显像/计算机断层显像(18F-FDG-PET/CT)预测食管鳞癌患者转移淋巴结(mLN)对放化疗的临床反应，指导个体化放疗剂量。该研究包括来自59名接受dCRT治疗并接受过治疗前18F-FDG-PET/CT扫描的ESCC患者的143名mLN。所有定义的MLN均由核医学放射科医生绘制轮廓。通过对比增强计算机断层扫描和18F-FDG-PET/CT评估反应。69个mLN显示完全反应(CR)，74个mLN显示非完全反应。 根据最大标准化摄取值（SUVmax-G1、SUVmax-G2、SUVmax-G3和SUVmax-G4）和代谢肿瘤体积（MTV-G1、 MTV-G2、MTV-G3 和 MTV-G4）。SUVmax-G2的CR率明显高于其他3组。增加的辐射剂量提高了SUVmax-G3(55Gy)和SUVmax-G4(61Gy)淋巴结的CR率。最低CR率出现在MTV-G4（MTV最大的组）中。增加的辐射剂量 (59.7Gy) 提高了MTV组3和4中淋巴结的CR率。
", "ds_process_way": "该研究包括来自59名接受dCRT治疗并接受过治疗前18F-FDG-PET/CT扫描的ESCC患者的143名mLN。所有定义的MLN均由核医学放射科医生绘制轮廓。通过对比增强计算机断层扫描和18F-FDG-PET/CT评估反应。
", "ds_quality": "数据质量良好
", "ds_acq_start_time": "2017-07-01 00:00:00", "ds_acq_end_time": "2019-12-31 00:00:00", "ds_acq_place": "甘肃兰州", "ds_acq_lon_east": null, "ds_acq_lat_south": null, "ds_acq_lon_west": null, "ds_acq_lat_north": null, "ds_acq_alt_low": null, "ds_acq_alt_high": null, "ds_share_type": "apply-access", "ds_total_size": 2355685, "ds_files_count": 2, "ds_format": "pdf", "ds_space_res": null, "ds_time_res": "", "ds_coordinate": "无", "ds_projection": "", "ds_thumbnail": "19aa28c9-1f92-456a-ac3f-96e6e5c9b595.png", "ds_thumb_from": 0, "ds_ref_way": "", "paper_ref_way": "", "ds_ref_instruction": "", "ds_from_station": null, "organization_id": "9971252d-7beb-4464-bc08-bdcc5a1d7dd1", "ds_serv_man": "敏玉芳", "ds_serv_phone": "0931-4967596", "ds_serv_mail": "ncdc@lzb.ac.cn", "doi_value": "", "subject_codes": [], "quality_level": 3, "publish_time": "2023-07-19 11:00:32", "last_updated": "2023-07-21 02:10:05", "protected": false, "protected_to": null, "lang": "zh", "cstr": "11738.11.NCDC.IMP.DB2900.2023", "i18n": { "en": { "title": "18 F-fluorodeoxyglucose positron emission tomography predicts lymph node responses to definitive chemoradiotherapy in esophageal squamous cell carcinoma patients", "ds_format": "", "ds_source": "The purpose of this study was to evaluate the value of 18F-FDG-PET / CT in predicting the clinical response of metastatic lymph nodes (MLN) in patients with esophageal squamous cell carcinoma to radiotherapy and chemotherapy, and to guide the individualized radiotherapy dose.
", "ds_quality": "Good data quality
", "ds_ref_way": "", "ds_abstract": "In this paper, functional imaging PET-CT was used to guide the delineation of esophageal cancer target area, and the accuracy of delineation of esophageal cancer lymph nodes by different images was compared. Pathology confirmed that PET-CT was superior to CT in delineation of lymph nodes. Based on the CT image and PET / CT fusion image, the tumor target area is delineated and the precise radiotherapy plan is made. Based on the PET / CT fusion image, the target area is more accurate and the radiotherapy is more accurate, avoiding the excessive damage of normal tissue. CT combined with PET-CT dual positioning, functional imaging intervention improves the accuracy of target delineation.
", "ds_time_res": "", "ds_acq_place": "Lanzhou, Gansu", "ds_space_res": "", "ds_projection": "", "ds_process_way": "", "ds_ref_instruction": "" } }, "submit_center_id": "ncdc", "data_level": 0, "recommendation_value": 0, "license_type": "https://creativecommons.org/licenses/by/4.0/", "doi_reg_from": "reg_local", "cstr_reg_from": "reg_local", "doi_not_reg_reason": null, "cstr_not_reg_reason": null, "is_paper_in_submitting": false, "belong_to_nieer": false, "ds_topic_tags": [ "PET-CT食管癌", "淋巴结", "病理" ], "ds_subject_tags": [], "ds_class_tags": [], "ds_locus_tags": [ "兰州", "甘肃省" ], "ds_time_tags": [ 2017, 2018, 2019 ], "ds_contributors": [ { "true_name": "肖国青", "email": "xiaogq@impcas.ac.cn", "work_for": "中国科学院近代物理研究所", "country": "中国" } ], "ds_meta_authors": [ { "true_name": "肖国青", "email": "xiaogq@impcas.ac.cn", "work_for": "中国科学院近代物理研究所", "country": "中国" } ], "ds_managers": [ { "true_name": "肖国青", "email": "xiaogq@impcas.ac.cn", "work_for": "中国科学院近代物理研究所", "country": "中国" } ], "category": "其他" }