针对国产高端稀土试剂品种少、纯度低、依赖进口等突出问题，以国家战略需求为导向，突破高纯度稀土手性稀土有机配合物试剂的制备技术难关和建立高纯稀土试剂定量分析方法后，进一步研究了所制备的高纯手性稀土配合物在科研和生产领域的应用，实现了其催化的7类不对称催化反应，并形成了相应的数据集。
", "ds_source": "本资源来源于手性稀土有机配合物不对称催化应用和光学产物纯度分析方法的研究过程。核磁共振、元素分析、手性HPLC、比旋光度数据均在北京化工大学采集。包括7类不对称催化反应的反应条件、产物结构及其表征数据和谱图，具体如下：
\n1.手性吡啶双噁唑啉铽催化的不对称Nazarov反应（实验步骤、表征数据、核磁和液相色谱图）
\n2.手性吡啶双噁唑啉铈催化的不对称6π电环化反应（实验步骤、表征数据、核磁和液相色谱图）
\n3.手性Salen钪催化的氮杂环丙烷与醛不对称(3 + 2)环加成反应（实验步骤、表征数据、核磁和液相色谱图）
\n4.手性希夫碱三氟甲磺酸钪催化的不对称Michael加成反应（实验步骤、表征数据、核磁和液相色谱图）
\n5.手性吡啶双噁唑啉镧催化的不对称Diels-Alder环加成反应（实验步骤、表征数据、核磁和液相色谱图）
\n6.手性希夫碱Salazin 钇催化的不对称aldol反应（实验步骤、表征数据、核磁和液相色谱图）
\n7.手性酚骨架双脯氨酸酯镧催化的多取代手性环丁烯的合成（实验步骤、表征数据、核磁和液相色谱图）
", "ds_process_way": "基于核磁共振波谱技术，采用Bruker AV Neo 400M液态超导核磁共振谱仪，在合适的氘代试剂中对待测化合物进行1H、13C或19F谱的测试，采用MestReNova进行数据处理，根据波谱峰的化学位移判断化学结构。采用Agilent LC/MSD TOF高分辨质谱仪测定产物的精确分子量，利用Agilent Technologies 1260 Infinity 手性液相色谱仪测量产物的光学纯度（ee值），采用Anton Paar MCP500比旋光仪测定比旋光仪度。相关测定方法均为行业内广泛接受并采用的方法。
", "ds_quality": "本数据源采用行业内广泛认可、广泛采用的有机化合物分析测试方法。依据JJF1855-2020 《纯度标准物质定值计量技术规范 有机物纯度标准物质等标准规范》的要求进行手性HPLC测试。本资源相关数据采集自北京化工大学合成实验室，时间跨度与整个方法研发周期同步。通过严格规范合成实验过程和反应条件，并通过多人、多次验证，保障数据采集的可靠性和合成过程的标准化。相关数据已通过同行评审，发表在国际知名或一流期刊上。
", "ds_acq_start_time": "2022-11-01 00:00:00", "ds_acq_end_time": "2025-12-31 00:00:00", "ds_acq_place": "", "ds_acq_lon_east": null, "ds_acq_lat_south": null, "ds_acq_lon_west": null, "ds_acq_lat_north": null, "ds_acq_alt_low": null, "ds_acq_alt_high": null, "ds_share_type": "apply-access", "ds_total_size": 90925832, "ds_files_count": 0, "ds_format": "*.pdf", "ds_space_res": "", "ds_time_res": "", "ds_coordinate": "无", "ds_projection": "", "ds_thumbnail": "20dcda02-82c8-4a51-ac7e-8a40fa66d411.png", "ds_thumb_from": 2, "ds_ref_way": "", "paper_ref_way": "", "ds_ref_instruction": "", "ds_from_station": "", "organization_id": "af683ce0-400b-4f2f-9242-f45f0621e11a", "ds_serv_man": "李红星", "ds_serv_phone": "0931-4967592", "ds_serv_mail": "ncdc@lzb.ac.cn", "doi_value": "", "subject_codes": [ "410" ], "quality_level": 0, "publish_time": "2026-05-21 15:35:56", "last_updated": "2026-05-21 15:35:56", "protected": false, "protected_to": null, "lang": "zh", "cstr": "", "i18n": { "en": { "title": "Analytical data for 7 types of chiral organic ligand—rare-earth complexescatalyzed seven types of asymmetric catalytic reactions", "ds_format": "*.pdf", "ds_source": "This resource comes from the research process of asymmetric catalytic applications of chiral rare earth organic complexes and optical product purity analysis methods. Nuclear magnetic resonance, elemental analysis, chiral HPLC, and specific optical rotation data were collected at Beijing University of Chemical Technology. Including the reaction conditions, product structures, characterization data, and spectra of 7 types of asymmetric catalytic reactions, as follows:
", "ds_quality": "This data source adopts widely recognized and widely used organic compound analysis and testing methods in the industry. Perform chiral HPLC testing in accordance with the requirements of JJF1855-2020 \"Technical Specification for Quantitative Measurement of Purity Standard Substances - Organic Purity Standard Substances and Other Standard Specifications\". The data related to this resource was collected from the Synthesis Laboratory of Beijing University of Chemical Technology, and the time span was synchronized with the entire method development cycle. By strictly regulating the synthesis experiment process and reaction conditions, and through multiple verifications by multiple people, the reliability of data collection and standardization of the synthesis process are ensured. The relevant data has been peer-reviewed and published in internationally renowned or top tier journals.
", "ds_ref_way": "", "ds_abstract": "In response to the prominent problems of limited varieties, low purity, and dependence on imports of domestically produced high-end rare earth reagents, guided by national strategic needs, we have overcome the technical difficulties in preparing high-purity rare earth chiral rare earth organic complex reagents and established a quantitative analysis method for high-purity rare earth reagents. We have further studied the application of the prepared high-purity chiral rare earth complexes in scientific research and production fields, achieved seven types of asymmetric catalytic reactions catalyzed by them, and formed corresponding datasets.
", "ds_time_res": "", "ds_acq_place": "", "ds_space_res": "", "ds_projection": "", "ds_process_way": "Based on nuclear magnetic resonance spectroscopy technology, Bruker AV Neo 400M liquid superconducting nuclear magnetic resonance spectrometer was used to test the 1H, 13C or 19F spectra of the test compound in suitable deuterated reagents. MestReNova was used for data processing, and the chemical structure was determined based on the chemical shift of the spectral peaks. The precise molecular weight of the product was determined using an Agilent LC/MSD TOF high-resolution mass spectrometer, the optical purity (ee value) of the product was measured using an Agilent Technologies 1260 Infinity chiral liquid chromatograph, and the specific rotation was measured using an Anton Paar MCP500 polarimeter. The relevant measurement methods are widely accepted and adopted in the industry.
", "ds_ref_instruction": "" } }, "submit_center_id": "ncdc", "data_level": 0, "recommendation_value": 0, "license_type": "https://creativecommons.org/licenses/by/4.0/", "doi_reg_from": "reg_local", "cstr_reg_from": "reg_local", "doi_not_reg_reason": null, "cstr_not_reg_reason": null, "is_paper_in_submitting": false, "ds_topic_tags": [ "高催化性能手性稀土配合物", "7类不对称催化反应", "分析数据" ], "ds_subject_tags": [ "工程与技术科学基础学科" ], "ds_class_tags": [], "ds_locus_tags": [], "ds_time_tags": [], "ds_contributors": [ { "true_name": "许家喜", "email": "jxxu@buct.edu.cn", "work_for": "北京化工大学", "country": "中国" }, { "true_name": "杨占会", "email": "zhyang@buct.edu.cn", "work_for": "北京化工大学", "country": "中国" } ], "ds_meta_authors": [ { "true_name": "杨占会", "email": "zhyang@buct.edu.cn", "work_for": "北京化工大学", "country": "中国" } ], "ds_managers": [ { "true_name": "杨占会", "email": "zhyang@buct.edu.cn", "work_for": "北京化工大学", "country": "中国" } ], "category": "其他" }