该报告是一份多模式引导的粒子治疗新技术研究及实现的方案，该方案主要介绍多种模式引导下，如图像引导、视听反馈等，综合多种信息，引导粒子治疗过程，实现粒子的精准放射治疗，促进放疗发展，进行放疗的新技术研究及实现。
", "ds_source": "本研究建立了基于体表位置的光学图像摆位验证方法，进而在安装了光学图像和X射线图像引导硬件的实验终端，进行了图像引导的碳离子治疗技术的验证。研发了生物视听反馈呼吸引导门控技术，可大幅减小门控窗内的靶区残余运动，达到了提高了重离子束治疗的精度的目的；所发展的呼吸引导可使呼吸门控技术的治疗效率提高5~6倍，可将治疗精度提高10倍左右。在磁引导粒子治疗技术方面，通过实验测量了磁场情况下碳离子束的偏转情况；在磁共振成像实时技术方面，目前实现了每秒10帧图像的连续观察，并对荷瘤小鼠和无瘤大鼠进行了实时成像观察。
", "ds_process_way": "此报告是项目的汇总报告，其中的位置数据通过软件读取，剂量数据采用物理剂量计测量，模拟工具用的是GATE和TOPAS。
", "ds_quality": "数据质量良好。
", "ds_acq_start_time": "2017-07-01 00:00:00", "ds_acq_end_time": "2019-12-31 00:00:00", "ds_acq_place": "甘肃兰州", "ds_acq_lon_east": null, "ds_acq_lat_south": null, "ds_acq_lon_west": null, "ds_acq_lat_north": null, "ds_acq_alt_low": null, "ds_acq_alt_high": null, "ds_share_type": "apply-access", "ds_total_size": 50345534, "ds_files_count": 2, "ds_format": "pdf", "ds_space_res": null, "ds_time_res": "", "ds_coordinate": "无", "ds_projection": "", "ds_thumbnail": "86346c19-0be0-4b73-958f-9f1a43555fae.png", "ds_thumb_from": 0, "ds_ref_way": "", "paper_ref_way": "", "ds_ref_instruction": "", "ds_from_station": null, "organization_id": "9971252d-7beb-4464-bc08-bdcc5a1d7dd1", "ds_serv_man": "敏玉芳", "ds_serv_phone": "0931-4967596", "ds_serv_mail": "ncdc@lzb.ac.cn", "doi_value": "", "subject_codes": [], "quality_level": 3, "publish_time": "2023-09-21 15:34:36", "last_updated": "2023-09-21 15:34:36", "protected": false, "protected_to": null, "lang": "zh", "cstr": "11738.11.NCDC.IMP.DB3986.2023", "i18n": { "en": { "title": "Research and implementation of new technology of multi-mode guided particle therapy", "ds_format": "", "ds_source": " In this study, an optical image positioning verification method based on body surface position is established, and then the image-guided carbon ion therapy technology is verified in the experimental terminal with optical image and X-ray image-guided hardware. We developed the bio audio-visual feedback respiratory guidance gating technology, which can greatly reduce the residual motion of the target area in the gating window, and achieve the purpose of improving the accuracy of heavy ion beam therapy; The developed respiratory guidance can improve the therapeutic efficiency of respiratory gating technology by 5 ~ 6 times and the therapeutic accuracy by 10 times. In the aspect of magnetically guided particle therapy, the deflection of carbon ion beam in magnetic field was measured experimentally; In the aspect of real-time MRI technology, we have achieved continuous observation of 10 frames per second, and real-time imaging observation of tumor bearing mice and tumor free rats.\n Good data quality\n This report is a multi-mode guided particle therapy new technology research and implementation scheme. The scheme mainly introduces the multi-mode guidance, such as image guidance, audio-visual feedback, etc., which integrates a variety of information to guide the particle therapy process, realize the particle precision radiotherapy, promote the development of radiotherapy, and carry out the research and implementation of new technology of radiotherapy.\n This report is a summary report of the project, in which the location data is read by software, the dose data is measured by physical dosimeter, and the simulation tools are gate and Topas.\n